The project focuses on the study of secondary processing techniques applied to difficult-to-machine alloys for surface functionalization purposes. Specifically, it investigates the machining of titanium and magnesium alloys for biomedical use, aimed at regulating tissue-implant interaction, as well as the impact of such processes on the adhesion behavior of biomedical coatings, which are also intended for differential drug delivery. To date, experimental activities have been conducted using milling, electrical discharge machining (EDM), sandblasting, and laser texturing, along with the characterization of surface integrity of the components and the adhesion of biopolymer-based coatings. The project has a twofold objective: (i) improving coating adhesion to control the degradation of magnesium alloys and enhance the biological response of implantable devices; and (ii) providing a preliminary assessment of the effect of surface treatments on cellular behavior, serving as a foundation for further studies on implant-body environment interaction.
English 
Italian